DNA Fingerprinting - Unsolved Practice Set
Chapter: Molecular Basis of Inheritance | Topic: DNA Fingerprinting
DNA FINGERPRINTING - UNSOLVED PRACTICE SET
Topic: DNA Fingerprinting
Multiple Choice Questions
Q1. DNA fingerprinting relies primarily on the analysis of:
- Coding regions of genes only
- Variable Number Tandem Repeats (VNTRs), also called satellite DNA
- Ribosomal RNA sequences only
- Mitochondrial proteins
Q2. The technique of DNA fingerprinting was originally developed by:
- Watson and Crick
- Alec Jeffreys
- Hershey and Chase
- Meselson and Stahl
Q3. Which technique is commonly used to separate DNA fragments by size during DNA fingerprinting?
- PCR alone
- Gel electrophoresis
- X-ray crystallography
- Chromatography
Q4. DNA fingerprinting is especially useful in forensic science because VNTR patterns are:
- Identical in all individuals
- Highly variable between individuals (except identical twins)
- Present only in bacteria
- Not inheritable
Q5. In India, DNA fingerprinting technology was notably developed and applied through the efforts of:
- C.V. Raman
- Dr. Lalji Singh
- Homi Bhabha
- Salim Ali
Short Answer Questions
Q6. What is DNA fingerprinting, and on what genetic feature does it primarily rely?
Q7. Why is DNA fingerprinting considered so reliable for identifying individuals, apart from identical twins?
Q8. Name any two practical applications of DNA fingerprinting.
Q9. Briefly describe the role of gel electrophoresis in the DNA fingerprinting process.
Long Answer Questions
Q10. Describe the general steps involved in the DNA fingerprinting technique, from DNA extraction to the final identification pattern.
Q11. Discuss the various applications of DNA fingerprinting in forensic science, paternity testing, and other fields, explaining why it has become such an important tool.
APPLICATION / ANALYSIS
Q12. In a paternity dispute case, a DNA fingerprinting test is conducted comparing the child's DNA pattern with that of the alleged father and mother. Explain, using your understanding of VNTR inheritance, how matching band patterns between the child and the alleged father would support the paternity claim.
Q13. At a crime scene, investigators recover a small blood sample and compare its DNA fingerprint with that of a suspect. Explain why even a very small amount of biological sample can be sufficient for reliable DNA fingerprinting analysis, considering modern amplification techniques.