Transcription in Eukaryotes - Unsolved Practice Set
Chapter: Molecular Basis of Inheritance | Topic: Transcription in Eukaryotes
TRANSCRIPTION IN EUKARYOTES - UNSOLVED PRACTICE SET
Topic: Transcription in Eukaryotes
Multiple Choice Questions
Q1. Unlike prokaryotes, eukaryotic cells use how many major types of RNA polymerase for transcription?
- One
- Two
- Three
- Four
Q2. In eukaryotes, RNA polymerase II is primarily responsible for transcribing:
- rRNA
- tRNA and small RNAs
- hnRNA/mRNA (the precursor of mRNA)
- Ribosomal proteins
Q3. The primary transcript formed in eukaryotic cells, before processing, is called:
- mRNA directly
- hnRNA (heterogeneous nuclear RNA)
- tRNA
- rRNA
Q4. The removal of non-coding sequences (introns) and joining of coding sequences (exons) from hnRNA is called:
- Capping
- Splicing
- Tailing
- Translation
Q5. The addition of a poly-A tail to the 3' end of hnRNA is an example of:
- Splicing
- Post-transcriptional processing/modification
- Translation
- Replication
Short Answer Questions
Q6. Name the three major RNA polymerases found in eukaryotic cells, along with the type of RNA each transcribes.
Q7. What is hnRNA, and how is it different from mature mRNA?
Q8. Briefly explain what is meant by "capping" and "tailing" during mRNA processing in eukaryotes.
Q9. Define splicing, and explain its significance in eukaryotic gene expression.
Long Answer Questions
Q10. Describe the process of hnRNA processing in eukaryotes, explaining capping, tailing, and splicing in sequence.
Q11. Discuss how transcription in eukaryotes differs from transcription in prokaryotes, mentioning at least three key differences.
APPLICATION / ANALYSIS
Q12. A gene in a eukaryotic cell contains several introns interspersed between exons. If splicing fails to occur properly and the introns remain in the mRNA, predict what problem this could cause during protein synthesis.
Q13. A researcher compares transcription in a bacterial cell and a human cell for the same type of hypothetical gene. Explain why the human cell's transcription process would require additional processing steps that the bacterial cell's transcript would not need.